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Nautilai Plus

The New Standard in Functional Biology. Multimodal and Scalable.

The first multimodal platform to unify contractility, optical readouts, and synchronized video at 96-well scale and beyond.

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Make high-throughput contractility your primary endpoint.
Retain access to scalable fluorescence.

Purpose-built for drug development teams running functional 3D tissue drug testing, IC50/EC50 potency assays, toxicity screening — with 96-well contractility and up to 1536-well fluorescence in the same instrument.

More data, less effort.

  • 96-well scale and beyond, designed so your team focuses on results, not repetition.

From experiment to answer, faster.

  • Automated workflows reduce setup time so you can focus on the decisions that matter.

See it to believe it.

  • Tissue video synchronized with your data gives you instant visual confirmation of every result.

One platform. Your entire research program.

  • Cardiac, skeletal muscle, neuronal, and neuromuscular models. 2D cultures, organoids, and 3D tissues. One instrument.
 
 

One Workflow. Countless Functional Assays.

From the moment you press record to the moment you make a decision — Nautilai Plus and Pulse work together so nothing gets left behind.

What Nautilai Plus Sees

  • Measure contractility and baseline tissue state

  • Capture Ca2+ and voltage amplitude and kinetics

  • Apply and synchronize stimulation protocols

  • Validate visually via synchronized tissue video

What Pulse Delivers

  • Automatic waveform processing and metrics extraction

  • Standardized outputs across force, beat rate, and calcium

  • Concise, shareable formatting for team review

  • Flexible cloud access and cross-team collaboration

 
 

Part of an Ecosystem

 

96-well Nautilai Plate

Consumable

Purpose-built for long-term 3D tissue culture and automation-compatible workflows.

Stingray™

Electrical Stimulation

Precise pacing at 24- or 96-well scale — autonomously, inside your incubator.

Cells & Media

Biological Solutions

Validated protocols optimized for Cardiac, Skeletal, and NMJ models on Nautilai Plus.

 
 

 Explore Applications

High-Throughput Neuroactivity Profiling with Nautilai – Quantitative Calcium Transient Analysis in CNS-3D Brain Organoids

Scalable Functional Screening of AAV Capsids in 3D Engineered Skeletal Muscle

Additional application notes in development across neuromuscular, disease models, 3D tissue drug testing, and more. Contact us to discuss your model