This publication demonstrates that cells can transmit forces by coupling the retrograde flow of actin to a geometrically irregular environment, and that this can happen in the complete absence of any transmembrane receptors that link the cytoskeleton to the substrate.
Source: Reversat, A., Gaertner, F., Merrin, J. et al. Cellular locomotion using environmental topography. Nature 582, 582–585 (2020). (Link to Paper)
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